小州 发表于 2024-4-23 11:01:07

官宣!义乌爱尔眼科医院重磅开售【低浓度阿托品滴眼液】!

<!----><style type="text/css">html{font-size:375%}</style><link href="https://pics.app.cnyw.net/static/publish/css/style.css?v=1605251010503" rel="stylesheet" position="1" data-qf-origin="/static/publish/css/style.css?v=1605251010503"><!--    付费贴-->    <div class="preview_article ">            <!---->    <section style="font-size: 15px; letter-spacing: 1px; padding: 0px; box-sizing: border-box; font-style: normal; font-weight: 400; text-align: justify;"><p class="empty_paragraph" style="margin-bottom: 0px; letter-spacing: 0.578px; text-wrap: wrap;">&nbsp;</p><p style="margin-bottom: 0px; letter-spacing: 0.578px; text-wrap: wrap; font-family: system-ui, -apple-system, BlinkMacSystemFont, Helvetica Neue, PingFang SC, Hiragino Sans GB, Microsoft YaHei UI, Microsoft YaHei, Arial, sans-serif; background-color: #ffffff;">&nbsp;</p><p class="empty_paragraph" style="margin-bottom: 0px; letter-spacing: 0.578px; text-wrap: wrap; font-family: system-ui, -apple-system, BlinkMacSystemFont, Helvetica Neue, PingFang SC, Hiragino Sans GB, Microsoft YaHei UI, Microsoft YaHei, Arial, sans-serif; background-color: #ffffff;">&nbsp;</p><section style="text-align: center; margin-top: 10px; margin-bottom: 10px; line-height: 0; box-sizing: border-box;"><section style="max-width: 100%; vertical-align: middle; display: inline-block; line-height: 0; width: 90%; height: auto; box-sizing: border-box;"><img class="rich_pages wxw-img" style="vertical-align: middle; max-width: 100%; width: 100%; box-sizing: border-box; height: auto !important;" src="https://pics.app.cnyw.net/Fi-Gno-RFJAgEYvGtJWEDNIPDXjL" width="100%" /></section></section><section style="letter-spacing: 2px; padding: 0px 15px; line-height: 2; box-sizing: border-box;"><p style="margin: 0px 0px 1px; white-space: normal; padding: 0px; box-sizing: border-box;">&nbsp;</p><p style="margin: 0px 0px 1px; text-indent: 2.2667em; white-space: normal; padding: 0px; box-sizing: border-box;">作为国内正式获批用于延缓儿童近视进展的药物,0.01%硫酸阿托品滴眼液可延缓近视进展,降低高度近视、病理性近视的风险。且其使用方式简便,灵活,特别是联合光学手段协同增效,可进一步提升近视防控的效果。</p></section><section style="text-align: center; margin-top: 10px; margin-bottom: 10px; line-height: 0; box-sizing: border-box;"><section style="max-width: 100%; vertical-align: middle; line-height: 0; box-sizing: border-box;"></section></section><section style="letter-spacing: 2px; padding: 0px 15px; line-height: 2; box-sizing: border-box;"><p style="text-indent: 2.2667em; white-space: normal; margin: 0px; padding: 0px; box-sizing: border-box;"><span style="color: #fc0808; font-size: 16px; box-sizing: border-box;"><strong style="box-sizing: border-box;">目前,义乌爱尔眼科医院已引进国内首批0.01%硫酸阿托品滴眼液,并正式投入临床使用,可扫码添加客服咨询,或到院了解详情。</strong></span></p></section><section style="text-align: center; margin-top: 10px; margin-bottom: 10px; line-height: 0; box-sizing: border-box;"><section style="max-width: 100%; vertical-align: middle; display: inline-block; line-height: 0; width: 50%; height: auto; box-sizing: border-box;"><img class="rich_pages wxw-img" style="vertical-align: middle; max-width: 100%; width: 299px; box-sizing: border-box; height: auto !important;" src="https://pics.app.cnyw.net/FqZ4_hJ2mlcmbC062Ja6JolbJsoY" /></section></section><section style="letter-spacing: 2px; padding: 0px 15px; line-height: 2; box-sizing: border-box;"><p style="white-space: normal; margin: 0px; padding: 0px; box-sizing: border-box;">&nbsp;</p></section><section style="text-align: center; justify-content: center; display: flex; flex-flow: row nowrap; margin: 20px 0px 10px; box-sizing: border-box;"><section style="display: inline-block; vertical-align: bottom; width: auto; min-width: 5%; max-width: 100%; flex: 0 0 auto; height: auto; align-self: flex-end; margin: 0px -15px 0px 0px; box-sizing: border-box;"></section><section style="display: inline-block; vertical-align: bottom; width: auto; align-self: flex-end; flex: 0 0 auto; min-width: 5%; max-width: 100%; height: auto; background-color: #ff989f; padding: 8px 20px 8px 27px; margin: 0px -11px 0px 0px; box-sizing: border-box;"><section style="color: #ffffff; font-size: 16px; box-sizing: border-box;"><p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">阿托品&ne;&ldquo;近视神药&rdquo;</strong></p><p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">需遵医嘱,切勿盲目跟风</strong></p></section></section><section style="display: inline-block; vertical-align: top; width: auto; min-width: 5%; max-width: 100%; flex: 0 0 auto; height: auto; align-self: flex-start; box-sizing: border-box;"><section style="margin: -6px 0px 0px; box-sizing: border-box;"><section style="display: inline-block; width: 22px; height: 22px; vertical-align: top; overflow: hidden; background-color: #a3bff6; border-radius: 220px; box-sizing: border-box;"><section style="transform: rotateZ(315deg); -webkit-transform: rotateZ(315deg); -moz-transform: rotateZ(315deg); -o-transform: rotateZ(315deg); box-sizing: border-box;"><section style="transform: translate3d(8px, 0px, 0px); -webkit-transform: translate3d(8px, 0px, 0px); -moz-transform: translate3d(8px, 0px, 0px); -o-transform: translate3d(8px, 0px, 0px); margin: 8px 0px 0px; box-sizing: border-box;"><section style="display: inline-block; width: 13px; height: 8px; vertical-align: top; overflow: hidden; border-style: solid; border-width: 0px 0px 2px 2px; border-color: #ffffff; box-sizing: border-box;"><section style="text-align: justify; box-sizing: border-box;"><p style="white-space: normal; margin: 0px; padding: 0px; box-sizing: border-box;">&nbsp;</p></section></section></section></section></section></section></section></section><p style="white-space: normal; margin: 0px; padding: 0px; box-sizing: border-box;">&nbsp;</p><section style="letter-spacing: 2px; padding: 0px 15px; line-height: 2; box-sizing: border-box;"><p style="margin: 0px 0px 1px; text-indent: 2.2667em; white-space: normal; padding: 0px; box-sizing: border-box;">阿托品是一种抗胆碱药物,高浓度常被用于散瞳验光,低浓度可通过多种机制综合防控近视进展。</p><p style="text-align: center;"><img class="rich_pages wxw-img" style="height: auto !important;" src="https://pics.app.cnyw.net/Fkje8XAhS6YExUsZ0aJuOflglxBS" /></p><p style="margin: 0px 0px 1px; text-indent: 2.2667em; white-space: normal; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">《低浓度阿托品滴眼液在儿童青少年近视防控中的应用专家共识(2022)》表明:低浓度阿托品滴眼液经循证医学验证能有效延缓近视进展。0.01%阿托品滴眼液不良反应更小、反弹效应更低,是现阶段儿童青少年近视防控的合理浓度。</strong></p><p style="white-space: normal; margin: 0px; padding: 0px; box-sizing: border-box;">&nbsp;</p></section><section style="text-align: center; margin-top: 10px; margin-bottom: 10px; line-height: 0; box-sizing: border-box;"><section style="max-width: 100%; vertical-align: middle; line-height: 0; box-sizing: border-box;"><img class="rich_pages wxw-img" style="vertical-align: middle; max-width: 100%; width: 578px; box-sizing: border-box; height: auto !important;" src="https://pics.app.cnyw.net/Fid4og0gd8w5ASPSfP771fGBgjeR" /></section></section><section style="letter-spacing: 2px; padding: 0px 15px; line-height: 2; box-sizing: border-box;"><p style="margin: 0px 0px 1px; white-space: normal; padding: 0px; box-sizing: border-box;">&nbsp;</p></section><section style="text-align: left; justify-content: flex-start; display: flex; flex-flow: row nowrap; margin: 10px 0px; box-sizing: border-box;"><section style="display: inline-block; vertical-align: top; width: auto; min-width: 5%; max-width: 100%; flex: 0 0 auto; height: auto; align-self: stretch; box-sizing: border-box;"><section style="display: flex; width: 100%; flex-flow: column nowrap; box-sizing: border-box;"><section style="z-index: 1; box-sizing: border-box;"><section style="font-size: 18px; margin: 0px 0%; text-align: center; box-sizing: border-box;"><section style="display: inline-block; background-color: #ff989f; width: 1.8em; height: 1.8em; line-height: 1.8em; border-radius: 100%; margin-left: auto; margin-right: auto; font-size: 19px; color: #ffffff; box-sizing: border-box; border: 1px solid #ff989f;"><p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">Q</strong></p></section></section></section></section></section><section style="display: inline-block; vertical-align: top; width: auto; align-self: stretch; flex: 100 100 0%; height: auto; background-color: rgba(255, 152, 159, 0.11); margin: 0px 0px 0px -17px; padding: 0px 0px 0px 29px; box-sizing: border-box;"><section style="margin: 6px 0px 0px; box-sizing: border-box;"><section style="text-align: justify; color: #ff989f; box-sizing: border-box;"><p style="white-space: normal; margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;"><span style="font-size: 16px; box-sizing: border-box;">低浓度阿托品的适宜人群</span></strong></p></section></section></section></section><section style="text-align: left; justify-content: flex-start; display: flex; flex-flow: row nowrap; margin: 17px 0px 10px; box-sizing: border-box;"><section style="display: inline-block; vertical-align: top; width: auto; min-width: 5%; max-width: 100%; flex: 0 0 auto; height: auto; align-self: stretch; box-sizing: border-box;"><section style="display: flex; width: 100%; flex-flow: column nowrap; box-sizing: border-box;"><section style="z-index: 1; box-sizing: border-box;"><section style="font-size: 18px; margin: 0px 0%; text-align: center; box-sizing: border-box;"><section style="display: inline-block; background-color: #a3bff6; width: 1.8em; height: 1.8em; line-height: 1.8em; border-radius: 100%; margin-left: auto; margin-right: auto; font-size: 19px; color: #ffffff; box-sizing: border-box; border: 1px solid #a3bff6;"><p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">A</strong></p></section></section></section></section></section><section style="display: inline-block; vertical-align: top; width: auto; align-self: stretch; flex: 100 100 0%; height: auto; margin: 0px 0px 0px -17px; padding: 0px 26px 0px 29px; box-sizing: border-box;"><section style="margin: 0px; box-sizing: border-box;"><section style="text-align: justify; color: #303030; letter-spacing: 1.5px; line-height: 2; box-sizing: border-box;"><p style="white-space: normal; margin: 0px; padding: 0px; box-sizing: border-box;"><span style="color: #3e3e3e; box-sizing: border-box;">适用于延缓球镜度数为<strong style="box-sizing: border-box;">-1.00D至-4.00D(散光&le;1.50D、屈光参差&le;1.50D)的6至12岁儿童</strong>的近视进展。</span></p></section></section></section></section><section style="letter-spacing: 2px; padding: 0px 15px; line-height: 2; box-sizing: border-box;"><p style="margin: 0px 0px 1px; white-space: normal; padding: 0px; box-sizing: border-box;">&nbsp;</p></section><section style="text-align: left; justify-content: flex-start; display: flex; flex-flow: row nowrap; margin: 10px 0px; box-sizing: border-box;"><section style="display: inline-block; vertical-align: top; width: auto; min-width: 5%; max-width: 100%; flex: 0 0 auto; height: auto; align-self: stretch; box-sizing: border-box;"><section style="display: flex; width: 100%; flex-flow: column nowrap; box-sizing: border-box;"><section style="z-index: 1; box-sizing: border-box;"><section style="font-size: 18px; margin: 0px 0%; text-align: center; box-sizing: border-box;"><section style="display: inline-block; background-color: #ff989f; width: 1.8em; height: 1.8em; line-height: 1.8em; border-radius: 100%; margin-left: auto; margin-right: auto; font-size: 19px; color: #ffffff; box-sizing: border-box; border: 1px solid #ff989f;"><p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">Q</strong></p></section></section></section></section></section><section style="display: inline-block; vertical-align: top; width: auto; align-self: stretch; flex: 100 100 0%; height: auto; background-color: rgba(255, 152, 159, 0.11); margin: 0px 0px 0px -17px; padding: 0px 0px 0px 29px; box-sizing: border-box;"><section style="margin: 6px 0px 0px; box-sizing: border-box;"><section style="text-align: justify; color: #ff989f; box-sizing: border-box;"><p style="white-space: normal; margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;"><span style="font-size: 16px; box-sizing: border-box;">低浓度阿托品使用禁忌症</span></strong></p></section></section></section></section><section style="text-align: left; justify-content: flex-start; display: flex; flex-flow: row nowrap; margin: 17px 0px 10px; box-sizing: border-box;"><section style="display: inline-block; vertical-align: top; width: auto; min-width: 5%; max-width: 100%; flex: 0 0 auto; height: auto; align-self: stretch; box-sizing: border-box;"><section style="display: flex; width: 100%; flex-flow: column nowrap; box-sizing: border-box;"><section style="z-index: 1; box-sizing: border-box;"><section style="font-size: 18px; margin: 0px 0%; text-align: center; box-sizing: border-box;"><section style="display: inline-block; background-color: #a3bff6; width: 1.8em; height: 1.8em; line-height: 1.8em; border-radius: 100%; margin-left: auto; margin-right: auto; font-size: 19px; color: #ffffff; box-sizing: border-box; border: 1px solid #a3bff6;"><p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">A</strong></p></section></section></section></section></section><section style="display: inline-block; vertical-align: top; width: auto; align-self: stretch; flex: 100 100 0%; height: auto; margin: 0px 0px 0px -17px; padding: 0px 26px 0px 29px; box-sizing: border-box;"><section style="margin: 0px; box-sizing: border-box;"><section style="text-align: justify; color: #303030; letter-spacing: 1.5px; line-height: 2; box-sizing: border-box;"><p style="margin: 0px 0px 1px; white-space: normal; padding: 0px; box-sizing: border-box;"><span style="color: #3e3e3e; box-sizing: border-box;">莨菪碱成分过敏、患青光眼或有青光眼倾向、颅脑外伤、心脏病等人群禁用。</span></p><p style="white-space: normal; margin: 0px; padding: 0px; box-sizing: border-box;"><span style="color: #3e3e3e; box-sizing: border-box;">调节力低下、低色素者等慎用,部分伴有畏光症状的眼病可待痊愈后使用。</span></p></section></section></section></section><p style="white-space: normal; margin: 0px; padding: 0px; box-sizing: border-box;">&nbsp;</p><section style="text-align: left; justify-content: flex-start; display: flex; flex-flow: row nowrap; margin: 10px 0px; box-sizing: border-box;"><section style="display: inline-block; vertical-align: top; width: auto; min-width: 5%; max-width: 100%; flex: 0 0 auto; height: auto; align-self: stretch; box-sizing: border-box;"><section style="display: flex; width: 100%; flex-flow: column nowrap; box-sizing: border-box;"><section style="z-index: 1; box-sizing: border-box;"><section style="font-size: 18px; margin: 0px 0%; text-align: center; box-sizing: border-box;"><section style="display: inline-block; background-color: #ff989f; width: 1.8em; height: 1.8em; line-height: 1.8em; border-radius: 100%; margin-left: auto; margin-right: auto; font-size: 19px; color: #ffffff; box-sizing: border-box; border: 1px solid #ff989f;"><p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">Q</strong></p></section></section></section></section></section><section style="display: inline-block; vertical-align: top; width: auto; align-self: stretch; flex: 100 100 0%; height: auto; background-color: rgba(255, 152, 159, 0.11); margin: 0px 0px 0px -17px; padding: 0px 0px 0px 29px; box-sizing: border-box;"><section style="margin: 6px 0px 0px; box-sizing: border-box;"><section style="text-align: justify; color: #ff989f; box-sizing: border-box;"><p style="white-space: normal; margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;"><span style="font-size: 16px; box-sizing: border-box;">使用低浓度阿托品的注意事项</span></strong></p></section></section></section></section><section style="text-align: left; justify-content: flex-start; display: flex; flex-flow: row nowrap; margin: 17px 0px 10px; box-sizing: border-box;"><section style="display: inline-block; vertical-align: top; width: auto; min-width: 5%; max-width: 100%; flex: 0 0 auto; height: auto; align-self: stretch; box-sizing: border-box;"><section style="display: flex; width: 100%; flex-flow: column nowrap; box-sizing: border-box;"><section style="z-index: 1; box-sizing: border-box;"><section style="font-size: 18px; margin: 0px 0%; text-align: center; box-sizing: border-box;"><section style="display: inline-block; background-color: #a3bff6; width: 1.8em; height: 1.8em; line-height: 1.8em; border-radius: 100%; margin-left: auto; margin-right: auto; font-size: 19px; color: #ffffff; box-sizing: border-box; border: 1px solid #a3bff6;"><p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">A</strong></p></section></section></section></section></section><section style="display: inline-block; vertical-align: top; width: auto; align-self: stretch; flex: 100 100 0%; height: auto; margin: 0px 0px 0px -17px; padding: 0px 26px 0px 29px; box-sizing: border-box;"><section style="margin: 0px; box-sizing: border-box;"><section style="text-align: justify; color: #303030; letter-spacing: 1.5px; line-height: 2; box-sizing: border-box;"><p style="margin: 0px 0px 1px; white-space: normal; padding: 0px; box-sizing: border-box;"><span style="color: #3e3e3e; box-sizing: border-box;">◆0.01%硫酸阿托品属于处方用药,用药前需带孩子做全面规范的临床评估;</span></p><p style="margin: 0px 0px 1px; white-space: normal; padding: 0px; box-sizing: border-box;"><span style="color: #3e3e3e; box-sizing: border-box;">◆用药后需定期复诊:</span></p><p style="margin: 0px 0px 1px; white-space: normal; padding: 0px; box-sizing: border-box;"><span style="color: #3e3e3e; box-sizing: border-box;">◆评估用药后有无不良反应,是否可以继续用药;</span></p><p style="margin: 0px 0px 1px; white-space: normal; padding: 0px; box-sizing: border-box;"><span style="color: #3e3e3e; box-sizing: border-box;">◆评估近视控制效果,具体控制效果有个体差异,需要根据孩子的应答情况,调整用药方法等;</span></p><p style="white-space: normal; margin: 0px; padding: 0px; box-sizing: border-box;"><span style="color: #3e3e3e; box-sizing: border-box;">◆评估调节功能是否异常,是否需要配合训练等。</span></p></section></section></section></section><section style="letter-spacing: 2px; padding: 0px 15px; line-height: 2; box-sizing: border-box;"><p style="margin: 0px 0px 1px; white-space: normal; padding: 0px; box-sizing: border-box;">&nbsp;</p><p style="margin: 0px 0px 1px; text-indent: 2.2667em; white-space: normal; padding: 0px; box-sizing: border-box;">因此,家长如想给孩子使用低浓度阿托品滴眼液防控近视,<span style="color: #2d57ec; box-sizing: border-box;"><strong style="box-sizing: border-box;">需到专业医疗机构进行规范的临床评估、危险因素评估,由医生综合判断是否适用并遵医嘱指导使用</strong></span>。</p><p style="white-space: normal; margin: 0px; padding: 0px; box-sizing: border-box;">&nbsp;</p></section><section style="text-align: center; margin-top: 10px; margin-bottom: 10px; line-height: 0; box-sizing: border-box;"><section style="max-width: 100%; vertical-align: middle; line-height: 0; box-sizing: border-box;"><img class="rich_pages wxw-img" style="vertical-align: middle; max-width: 100%; width: 100%; box-sizing: border-box; height: auto !important;" src="https://pics.app.cnyw.net/FnX1-mtxi_U9S5fmWEcJd1RxKGKp" width="100%" /></section></section><section style="padding: 0px 15px; line-height: 2; box-sizing: border-box;"><p style="margin: 0px 0px 1px; white-space: normal; padding: 0px; box-sizing: border-box;">&nbsp;</p><p style="margin: 0px 0px 1px; text-indent: 2.1333em; white-space: normal; padding: 0px; box-sizing: border-box;">义乌爱尔眼科医院引进0.01%硫酸阿托品滴眼液后,可针对不同患者的具体情况,制定更加精准、个性化的治疗方案,从而更有效地控制青少年儿童近视度数的发展,为更多青少年儿童近视防控带来福音。</p><p>&nbsp;</p><p><span style="color: #888888; font-size: 12px;">参考文献</span></p><p><span style="color: #888888; font-size: 12px;">Kesarwani SS; Mumbai Group of Paediatric Ophthalmologists and Strabismologists. Consensus statement&nbsp;</span><span style="color: #888888; font-size: 12px;">and guidelines for use of dilute atropine sulphate in myopia control. Indian J Ophthalmol. 2019;67(4):461-463.</span><span style="color: #888888; font-size: 12px;">doi:10.4103/ijo.IJO_1457_18</span></p><p><span style="color: #888888; font-size: 12px;">Kinoshita N, Konno Y, Hamada N, et al. Efficacy of combined orthokeratology and 0.01% atropine solution</span><span style="color: #888888; font-size: 12px;">for slowing axial elongation in children with myopia: a 2-year randomised trial. Sci Rep.2020;10(1):12750.</span><span style="color: #888888; font-size: 12px;">Published 2020 Jul 29.doi:10.1038/s41598-020-69710-8</span></p><p><span style="color: #888888; font-size: 12px;">Nucci P, Lembo A, Schiavetti l, Shah R, Edgar DF, Evans BJW. A comparison of myopia control in European</span><span style="color: #888888; font-size: 12px;">children and adolescents with defocus incorporated multiple segments (DIMS) spectacles, atropine, and</span><span style="color: #888888; font-size: 12px;">combined DIMS/atropine.PLoS One.2023;18(2):e0281816. Published 2023 Feb 16. doi:10.1371/jour-</span><span style="color: #888888; font-size: 12px;">nal.pone.0281816</span></p><p><span style="color: #888888; font-size: 12px;">低浓度阿托品滴眼液在儿童青少年近视防控中的应用专家共识(2022)</span></p><section style="margin-bottom: 0px; text-wrap: wrap; text-align: center; outline: 0px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Helvetica Neue, PingFang SC, Hiragino Sans GB, Microsoft YaHei UI, Microsoft YaHei, Arial, sans-serif; letter-spacing: 0.544px; color: #474545; font-size: 15px; background-color: #ffffff; visibility: visible;"><section style="outline: 0px; color: #333333; letter-spacing: normal; font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, Arial, sans-serif;"><section style="outline: 0px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Helvetica Neue, PingFang SC, Hiragino Sans GB, Microsoft YaHei UI, Microsoft YaHei, Arial, sans-serif; letter-spacing: 0.544px; font-size: 14px;"><section style="outline: 0px;"><section class="empty_paragraph" style="outline: 0px; letter-spacing: 0.544px; text-align: start; caret-color: #000000; font-family: -apple-system, BlinkMacSystemFont, Arial, sans-serif;"></section><section style="outline: 0px; letter-spacing: 0.544px; text-align: start; caret-color: #000000; font-family: -apple-system, BlinkMacSystemFont, Arial, sans-serif;"></section></section></section></section></section><p class="empty_paragraph" style="margin-bottom: 0px; text-wrap: wrap; text-align: center; color: #333333; font-family: system-ui, -apple-system, BlinkMacSystemFont, Helvetica Neue, PingFang SC, Hiragino Sans GB, Microsoft YaHei UI, Microsoft YaHei, Arial, sans-serif; font-size: 14px; letter-spacing: 0.544px; background-color: #ffffff;">&nbsp;</p></section></section><p style="display: none;">&nbsp;</p>    <!----></div>            
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